For those in California, please contact your program manager or info@cmqcc.org with any questions about clinical recommendations for low-dose aspirin during pregnancy.
CMQCC, in partnership with March of Dimes, is collaborating with select hospitals and community organizations statewide to promote the use of daily low-dose aspirin for women and birthing people at risk for preeclampsia. Low-dose aspirin, as recommended by a healthcare provider, is the only known effective solution to prevent preeclampsia.
About Preeclampsia
According to the American College of Obstetricians and Gynecologists, preeclampsia is a disorder of pregnancy associated with new-onset hypertension, which occurs most often after 20 weeks of gestation and frequently near term. It affects about 4% of pregnancies in the United States and accounts for 6% of preterm births. Black women and birthing individuals are at greater risk for developing preeclampsia, due to heightened experiences of racism, further exacerbating disparities in maternal health outcomes.
Resources for Pregnant Women/People
- March of Dimes, "Learn about low dose aspirin during pregnancy"
- Patient Information Sheet: "Let's Do Aspirin! To keep baby and you safe from preeclampsia" in English, Spanish and Arabic
- Patient Poster: "Prevent Preeclampsia with Low Dose Aspirin" for use in clinics and waiting rooms in English, Spanish and Arabic
- Patient Scorecard: "Should I do aspirin...to keep me and my baby safe?" in English, Spanish and Arabic
NEW RESOURCE! Low-Dose Aspirin for Preeclampsia Prevention: Implementation Guide for Clinical Teams
CMQCC and March of Dimes developed a low-dose aspirin (LDA) implementation guide for clinical teams to help bridge the gap between guidelines and practice. This groundbreaking roadmap uses clinical team best practices, patient and community engagement, and data-driven quality improvement, plus real-world clinic examples, lessons learned from early adopters, and strategies for overcoming common clinical practice barriers, to guide teams in supporting pregnant and postpartum patients.
Download Low-Dose Aspirin for Preeclampsia Prevention: Implementation Guide for Clinical Teams
Upcoming Webinar: December 4, 2025
Join March of Dimes and California Maternal Quality Care Collaborative (CMQCC) on December 4, 2025, from 3:00-4:00 pm EST (12:00-1:00 pm PST) for the first session of a three-part webinar series, Understanding Preeclampsia Risk & Low-Dose Aspirin: A Global and US Perspective. The webinar will review the global and US prevalence, outcomes, and disparities of preeclampsia and introduce our new co-authored resource, “Low-Dose Aspirin for Preeclampsia Prevention: Implementation Guide for Clinical Teams.” Registration link coming soon.
Additional Resources for Prenatal Health Care Clinicians and Professionals
- Communicating with Patients: How to Talk About Preeclampsia and Low Dose Aspirin with Patients
- Continuing Medical Education: Low Dose Big Benefits: Raising Awareness of Low Dose Aspirin to Reduce the Negative Impacts of Preeclampsia (Free offering, 1.0 CME, CPE, and CNE)
- Findings: U.S. Preventive Task Force "Final Recommendation Preeclampsia Screening"
- Patient Information Sheet: "Let's Do Aspirin! To keep baby and you safe from preeclampsia" in English, Spanish and Arabic
- Patient Poster: "Prevent Preeclampsia with Low Dose Aspirin" for use in clinics and waiting rooms in English, Spanish and Arabic
- Patient Scorecard: "Should I do aspirin...to keep me and my baby safe?" in English, Spanish and Arabic
- Podcast: "Preventing Preterm Birth and Preeclampsia - Office Hours with Dr. Diana Ramos," featuring Dr. David K. Stevenson, professor of pediatrics at Stanford School of Medicine
- Publication: "Systemic Health Intervention Design through Participatory Modeling: Low-dose Aspirin for Women at Risk of Preeclampsia." (8/20/25)
- Slide Set: Mini Grand Rounds: Low-dose Aspirin (LDA) Campaign to Reduce Preeclampsia and Related Preterm Birth
- Toolkit for Hospitals: Improving Health Care Response to Hypertensive Disorders of Pregnancy Toolkit (an evidence-based QI toolkit includes a section on low-dose aspirin)
- Webinar Series:
Funding Acknowledgement
This work is generously funded by March of Dimes.
Shareable Resources from March of Dimes
Learn more about March of Dimes’ Low Dose, Big Benefits campaign.